Article 13219

Title of the article

MICROMETRIC CHANGES OF THE WALLS OF LARGE ARTERIES IN THE CONDITIONS
OF IMPAIRED CARBOHYDRATE METABOLISM 

Authors

Fedorova Mariya Gennad'evna, Candidate of medical sciences, associate professor, head of sub-department of clinical morphology and forensic medicine with a course of oncology, Medical Institute, Penza State University (40 Krasnaya Street, Penza, Russia), E-mail: fedorovamerry@gmail.com
Averkin Nikita Sergeevich, Assistant, sub-department of clinical morphology and forensic medicine with a course of oncology, Medical Institute, Penza State University (40 Krasnaya Street, Penza, Russia), E-mail: averkin.n@list.ru
Latynova Irina Vladimirovna, Candidate of biological sciences, associate professor, sub-department of clinical morphology and forensic medicine with a course of oncology, Medical Institute, Penza State University (40 Krasnaya Street, Penza, Russia), E-mail: latynovai@mail.ru
Kharitonov Evgeniy Aleksandrovich, Candidate of medical sciences, forensic medical expert, Regional Bureau of Forensic Medical Examination (1 Svetlaya street, Penza, Russia), E-mail: sudmed_penza@mail.ru
Pivovarov Evgeniy Viktorovich, Forensic medical expert, Regional Bureau of Forensic Medical Examination (1 Svetlaya street, Penza, Russia), E-mail: sudmed_penza@mail.ru 

Index UDK

616.13 

DOI

10.21685/2072-3032-2019-2-13 

Abstract

Background. The main causes of mortality in Russia, as well as in all developed countries of the world remain cardiovascular diseases (CVD). The risk of heart and vascular diseases is associated with the impact of classical cardiovascular factors on the human body. The aim of the work was to study the micrometric parameters of the vascular wall in conditions of impaired carbohydrate metabolism.
Materials and methods. Arteries from 35 deceased people at the age of 25 to 45 years old (men) and up to 55 years old (women). Time of death is no more than 24 hours. At the level of the abdominal aorta, as well as in the places of departure of the common carotid artery on the left and right, visually "clean" areas of 3-4 cm were cut off. The following micrometric parameters were studied: the thickness of the inner and middle layers (at magnification of 40 times); the percentage of elastic fibers per unit area; the percentage of smooth muscle cells per unit area (at an magnification of 400 times).
Results. Changes in the wall thickness of arteries and the ratio of elastic and smooth muscle components per unit area were revealed.
Conclusions. The obtained micrometric data demonstrate changes in the structure of the walls of large vessels associated with impaired carbohydrate metabolism. 

Key words

morphometry, arterial walls, cardiovascular pathology 

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References

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Дата создания: 06.09.2019 13:26
Дата обновления: 16.09.2019 08:19